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Drug and hormone free relief for period pain & mood

Science meets self-care. Cutting edge neurotechnology combined with ancient, time-tested practices for daily relief.

Balance

starts in the brain

Our award-winning solutions are designed to boost and balance your brain health across the cycle. It’s menstrual care that starts where your cycle really begins.

  • All natural, drug and hormone-free

  • Clinically tested, studied and validated

  • Holistic pairing of modern and ancient techniques

  • Smart cycle predictions to help you plan ahead

  • Feel better from home - just 20 minutes a day, a few days each cycle.

Balance

Why the brain

Neuroplasticity holds the key

Your brain is the connection between your hormones and how you feel. We use both active and passive strategies to balance brain activity across your cycle - leading to fewer up and downs, and more stable, sustainable menstrual cycles.

How hormones affect your brain across your cycle

We study PMS, PMDD, endometriosis, focus, mood and more

Personalized support through integrated wearables and software

Evidence

94% of our users feel better in just three months.*

"What if there was a drug-free and effective way to manage both menstrual pain and mood disorders?"
“I waited for my bleak day... the one I usually spend holding back tears... It didn’t come.”
“Samphire Neuroscience is redefining women’s health with brain-based wearables”

* Based on our clinically validated, double-blind study on Nettle™ (WIND 2024)

What we help with

Explore our perspectives on women’s health below.

Too often, systems treat symptoms in isolation. Samphire’s solutions work across the brain, body and cycle - connecting the dots between pain, mood, focus, hormones and more.

Endometriosis

Endometriosis

Highly prevalent chronic inflammation.

Premenstrual syndrome

Premenstrual Syndrome

Widespread but often overlooked mood and body shifts.

showing brain with gears

ADHD and Neurodiversity

Differences in focus and attention.

Neuroplasticity

Neuroplasticity

The brain's ability to reorganize and adapt through experience.

pmdd

Premenstrual Dysphoric Disorder

Severe PMS symptoms causing mood changes and physical discomfort.

Dysmenorrhea

Dysmenorrhea

Painful menstrual cramps that can disrupt daily activities.

Sleep and rest

Sleep and Rest

Supporting quality sleep to restore energy and balance.

Emotions and mood swings

Emotions and Mood Swings

Managing sudden mood shifts and emotional sensitivity.

Stress and anxiety

Stress and Anxiety

Reducing tension and calming the mind during the cycle.

Feel better
every day of every cycle.

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Nettle

United KingdomEuropean Union+47 countries

Buy from £449.00

Rent from £59.99 / month

Discover Nettle™ 
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Samphire

Global availability

£4.99 / month

£49.99 / year

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Lutea™

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Backed by science, proven by you.

These are the experiences of people using our solutions every day.

Read All Reviews
Steph - Testimonial

I'm four cycles in... and will never look back. The changes were gradual and cumulative, but by the third cycle I felt as though my life had completely changed, I haven't had to take a day off work due to PMDD symptoms since the second cycle of using Nettle.

Emma

Divya - Testimonial

I really love this company. It is weird to say I feel seen and cared for by them. I just don't think I have felt like this with any other business.

Rachel

Ally - Testimonial

Has been life-changing for me. It has significantly improved my mental health, not just during the intense phases of PMDD before my period. But I actually feel much better during the rest of my cycle, too.

Jasmin

Alison - Testimonial

Then in the third month, my PMS symptoms were reduced by 80%! I still have menstrual pain, but the intensity has decreased again a bit.

Moko

Blog

Our latest research

Our science and technology teams write extensively on why the brain matters in women’s health.

Read all articles