When your cycle turns against you.

PMDD impacts mood, focus, and energy through deep brain–hormone shifts. Samphire helps you track, understand, and regulate patterns with science-led, wearable tools.

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Understanding Premenstrual Dysphoric Disorder (PMDD)

Gain control over your PMDD journey

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Nettle™ x PMDD Symptoms

Nettle™ is a certified medical device, clinically proven to reduce menstrual pain. It also helps support focus and emotional regulation in the lead-up to your period.

Explore Nettle
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Samphire App x PMDD Symptoms

Track patterns, understand triggers, and access tools to help regulate mood, reduce overwhelm, and support your brain through each phase of your cycle.

Explore the Samphire App

Backed by Science, Proven by You

Has been life-changing for me. It has significantly improved my mental health, not just during the intense phases of PMDD before my period. But I actually feel much better during the rest of my cycle, too.

Jasmin

I really love this company. It is weird to say I feel seen and cared for by them. I just don't think I have felt like this with any other business.

Rachel

Then in the third month, my PMS symptoms were reduced by 80%! I still have menstrual pain, but the intensity has decreased again a bit.

Moko

I'm four cycles in... and will never look back. The changes were gradual and cumulative, but by the third cycle I felt as though my life had completely changed, I haven't had to take a day off work due to PMDD symptoms since the second cycle of using Nettle.

Emma

Discover our brain-based perspectives on women’s health conditions below.

Too often, systems treat symptoms in isolation. Samphire’s solutions work across the brain, body and cycle - connecting the dots between pain, mood, focus, hormones and more.

Endometriosis

Endometriosis

Highly prevalent chronic inflammation.

Premenstrual syndrome

Premenstrual Syndrome

Widespread but often overlooked mood and body shifts.

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ADHD and Neurodiversity

Differences in focus and attention.

Neuroplasticity

Neuroplasticity

The brain's ability to reorganize and adapt through experience.

pmdd

Premenstrual Dysphoric Disorder

Severe PMS symptoms causing mood changes and physical discomfort.

Dysmenorrhea

Dysmenorrhea

Painful menstrual cramps that can disrupt daily activities.

Sleep and rest

Sleep and Rest

Supporting quality sleep to restore energy and balance.

Emotions and mood swings

Emotions and Mood Swings

Managing sudden mood shifts and emotional sensitivity.

Stress and anxiety

Stress and Anxiety

Reducing tension and calming the mind during the cycle.