science

Bringing women’s healthcare out of the dark ages.

Applying brain-based technologies to the bodies science overlooked.

Why the brain?

Why the brain?

A new perspective starts in the brain, and results in real care.

Research Pipeline

Most women’s health conditions can be targeted through brain-based approaches. Even when the cause lies outside the brain, these approaches offer lasting symptom relief -- increasing patient dignity and control while deeper research continues.

Our flagship solution, Nettle, has been subject to multiple clinical trials, with a comprehensive pipeline of follow-up studies planned.

Women's health has been underfunded and overlooked.

Our Mission

Women's health has been underfunded and overlooked.

The system's catching up.

Women's health isn't niche. It's necessary.

We use neuroscience, clinical technology and thoughtful design to create tools that help you feel more clear, steady and in control. From brain fog, to burn out and beyond.

Pilots and Trials

We’re working with clinical partners, researchers and regulators around the world on a growing portfolio of clinical trials and healthcare system pilots. Below are just a few in progress or complete.

WIND logo

WIND

Testing Nettle™ for PMS and dysmenorrhea.

ENHANCE logo

ENHANCE

Studying Nettle™’s impact on endometriosis-related chronic pelvic pain.

PMDD logo

PMDD

Evaluating Nettle™ for Premenstrual Dysphoric Disorder.

RELIEF logo

RELIEF

Studying Nettle™’s impact on endometriosis-related chronic pelvic pain.

HOPE logo

HOPE

Investigating Nettle for pain, fatigue, and quality of life among endometriosis patients.

HOLD logo

HOLD

Evaluating the longer-term impact of Nettle™ for menstrual pain.

Our technologies are grounded in more than three decades of foundational research. A selection of papers, some written by our team and our advisors, and others from the broader community, can be found below.

Modulating Anxiety and Functional Capacity with Anodal tDCS Over the Left Dorsolateral Prefrontal Cortex in Primary Dysmenorrhea

Dutra, L. (et al)

2020

Clinical usability study of a home-based self-administration transcranial direct current stimulation for primary dysmenorrhea: A randomized controlled trial

Rodrigues, Y. (et al)

2024

Emotion-induced brain activation across the menstrual cycle in individuals with premenstrual dysphoric disorder and associations to serum levels of progesterone-derived neurosteroids

Stiernam, L. (et al)

2023

Transcranial direct current stimulation: a roadmap for research, from mechanism of action to clinical implementation

Chase, H. (et al)

2020

Safety of Transcranial Direct Current Stimulation in Neurorehabilitation

Ko, M. (et al)

2021

Development and testing of a novel IoT consumer tDCS device for the treatment of primary dysmenorrhea

Radyte, E. (et al)

2023

Safety of transcranial Direct Current Stimulation: Evidence Based Update 2016

Biksom, M. (et al)

2016

Development and testing of a novel IoT consumer tDCS device for the treatment of primary dysmenorrhea

Radyte, E. (et al)

2023

Premenstrual dysphoric disorder and changes in frontal alpha asymmetry

Baehr, E. (et al)

2004

Modelling and Preliminary Clinical Validation of Home-based Menstrual Neuromodulation Therapy

Radyte, E. (et al)

2024

Effects of Transcranial Direct Current Stimulation for Treatment of Primary Dysmenorrhea: Preliminary Results of a Randomized Sham-Controlled Trial

Pegado, R. et al

2020

The association between premenstrual dysphoric disorder and depression: A systematic review

Eccles, H. (et al)

2023

Transcranial direct current stimulation to reduce chronic pelvic pain in endometriosis: Phase II Randomized Controlled Clinical Trial

Mechsner, S. (et al)

2023