The human brain is an enigma. As neuroscientists, we are in awe of its capabilities to help us lead healthier lives. Our research is a testament to our dedication to helping you both understand and unlock your brain's full potential.
Modulating Anxiety and Functional Capacity with Anodal tDCS Over the Left Dorsolateral Prefrontal Cortex in Primary Dysmenorrhea
The purpose of this trial was to examine the impact of transcranial direct current stimulation (tDCS) targeting the dorsolateral prefrontal cortex (DLPFC) on anxiety and functionality in patients with primary dysmenorrhea. The study demonstrated significant improvement in mood for 84% of users, concluding that tDCS appears to be an effective therapeutic approach for improving anxiety and functionality in women with primary dysmenorrhea.
Effects of Transcranial Direct Current Stimulation for Treatment of Primary Dysmenorrhea: Preliminary Results of a Randomized Sham-Controlled Trial
The purpose of this trial was to explore the impact of transcranial direct current stimulation (tDCS) targeting the motor cortex (M1) on pain, mood, and physical performance in patients with primary dysmenorrhea (PDM). Over the course of one week, non-invasive brain stimulation (tDCS) reduced pain symptoms in 89% of participants, offering preliminary evidence of tDCS's potential in managing menstrual pain.
Modelling and Preliminary Clinical Validation of Home-based Menstrual Neuromodulation Therapy
Our study with Nettle measured the impact of brain stimulation on both pain and mood symptoms by targeting both the M1 and DLPFC during the five sessions our users underwent. In just one month’s use Nettle, results showed a 53% reduction in pain, a 34% improvement in mood, and an 11% improvement in function. This lays the groundwork for further research into Nettle, particularly over a three-month period, during which we anticipate further improvements in symptoms due to neuroplasticity effects.
Neurosurgeon focused on global public health. Also the founder of the podcast called ‘Science with Sanjula’ where she interviews world-leading scientists about big issues in global healthcare. She is helping Samphire translate our science into public impact.
Researcher from Universidade Federal do Rio Grande do Norte focused on neglected women's health conditions. Responsible for running Samphire's clinical trials.
World-leading chronic pain researcher from Universidade Federal do Rio Grande do Norte. He was the first person in the world to publish a paper on the topic of tDCS to treat pain in dysmenorrhea (menstrual pain).
Pyschologist and world-leading researcher on innovative clinical interventions. Currently the president of Harvard Alumni for Mental Health and is responsible for developing Samphire's cognitive science-based interventions.
Professor of Neuropsychiatry at Harvard and global PMDD neuroanatomy expert. He worked on one of the first pieces of research that showed that PMDD is a neurobiological condition, which laid the foundation for PMDD being recognised by the International Classification of Diseases.
A highly qualified and experienced Consultant Obstetrician and Gynaecologist, with subspecialty accreditation in Reproductive Medicine and Surgery. She brings invaluable expertise in chronic gynaecological conditions like endometriosis and PCOS, and is supporting our clinical efforts to advance medical research in the UK.
The Menstrual Pain-Brain Connection
Neuroplasticity as a tool for optimising menstrual health
Will Neuroimaging Revolutionise the Diagnosis of PMDD?
Periods, Productivity, and the Path to Progress
The Problem with Painkillers: They Weren't Made for Women
